Tuesday 26 August 2014

COLON: EOSINOPHILIC COLITIS


the blue circles indicate eosinophils, in this picture , the number is approximately 15.



HISTOLOGICAL FINDINGS IN EOSINOPHILIC COLITIS
1.-No crypt disarray or distortion (except in case secondary to ulcerative colitis or Crohn s disease).
2.-Increase in number or eosinophils, greater than 20 eosinophils/hpf, another authors use greater than 60/10hpf.
3.-Abnormal location of eosinophils: within epithelium  or basal (close to muscularis mucosae), and some degranulated.
4.- Clusters and degranulated eosinophils.

biblio:Odze RD, Goldblum JR: Surgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas, 2nd ed. Elsevier: Philadelfia 2009 and Greenson  Diagnostic Gastrointestinal and Liver Pathology ,Lippincott Williams &Wilkins, 2009.

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